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吃瓜新闻 University


Immunology

Immunologists explore how our bodies protect us from infections, diseases, and foreign substances. Through research, 吃瓜新闻 scientists are gaining a deeper understanding, finding better treatments, and implementing stronger preventions for everything from the flu to cancer.

Immunology has a wide impact

Defending the body from bacteria and viruses is only one of the roles of the immune system.

Researching the immune system

Discoveries about the immune system, many made at 吃瓜新闻, have contributed to therapies, treatments, and even cures for autoimmune and allergic diseases, cancers, viral infections, and more.


We know that if you don鈥檛 get enough sleep, there鈥檚 changes in your immune function. Your immune function is how you fight diseases.鈥

Elizabeth Klerman

Professor of neurology, 吃瓜新闻 Medical School

A woman wearing a white medical coat in a hospital room
Purple and blue clusters of mouse vagus nerve sensory cells.

Investigating immune overreactions

Researchers identified a protein that can , driving inflammation and tissue damage in a range of autoimmune and chronic inflammatory conditions. In other research, scientists discovered that vagus nerve cells that sense heat, irritation, and tissue damage also , which could help prevent immune-driven damage in flu and other viral infections.

A hand covered in dirt

Studying innate immunity

Ranging from physical barriers like the skin to antimicrobial molecules produced by cells, the innate immune system is the body’s first line of defense. Scientists have identified proteins in the innate immune system that may be , including ALS. Researchers are also studying , which cause diseases like COVID-19, influenza, and West Nile.

Bacteria

Exploring pathogen detection

Viruses, bacteria, and even certain kinds of cancers can rapidly mutate to try to escape our immune systems. Scientists are to learn how to better help our immune systems fight disease. Researchers are also , to learn when the immune system launches a response, leading to new ways to boost immune reactions.

An illustration of a T cell

Understanding immune cells

T cells are essential to the immune system, distinguishing between the body’s own tissues and harmful invaders. Research revealed how for T cells to “preview.” Scientists have also engineered an to help model neurological disorders, and learned that to the lungs鈥 mucosal lining.

Combating cancer

吃瓜新闻 scientists are pioneering ways to prevent, treat, and adapt to the evolving threat of cancer.


Explore the pioneering work

Unleashing the immune system to fight cancer

Married for 47 years, and scientific collaborators for about as long, Arlene Sharpe and Gordon Freeman have dedicated their careers to unraveling the mysteries of the immune system and fulfilling the long-elusive promise of cancer immunotherapy.

Supercharging cancer treatments

吃瓜新闻 researchers are expanding the current cancer immunotherapy treatments by to hinder the ability of immune cells, exploring ways to , and to better fight solid tumors.

Adapting as cancer adapts

吃瓜新闻 scientists are approaching the issue of cancer mutation in a number of ways, from creating that are resistant to therapeutic drugs, to finding .

Keeping cancer from coming back

Across 吃瓜新闻, researchers are looking into the possibilities of personalized cancer vaccines for patients with , , and .

Better understanding bacteria

Researchers studying gut bacteria learned how diet and gut microbes work together to build the human immune system.


We鈥檙e trying to understand the difference between protective and failed immunity to TB.鈥

Sarah Fortune

Professor of immunology and infectious diseases, 吃瓜新闻 T.H. Chan School of Public Health

Sarah Fortune
I want to understand how microbes affect our immunity and help protect us.鈥

Smita Gopinath

Assistant professor of immunology and infectious diseases, 吃瓜新闻 T.H. Chan School of Public Health

Smita Gopinath stands with her arms crossed in a lab by a whiteboard

Prevailing against viruses

吃瓜新闻 scientists are making huge advancements in the eons-long arms race between humans and viruses.

Yonatan Grad

Vaccinations are vital during measles outbreaks

Yonatan Grad, professor of immunology and infectious diseases at 吃瓜新闻 Chan School, explains that measles is extremely contagious, so those in proximity to the outbreaks should make sure that they have been vaccinated.

Finding new approaches to treat Long COVID

A cartoon of a person pushing a COVID virus up a hill

Utilizing a powerful preventative treatment against the AIDS virus

Roger Shapiro

Exploring a unique approach for targeting all flu strains

A sick person blowing their nose

Decreasing cervical cancer screening frequency through HPV vaccination

A woman getting a shot from a doctor

Strengthening efforts in pandemic preparedness and vaccine research

Kizzmekia Corbett-Helaire

Understanding why pandemics keep going

Powel Kazanjian